The effect of antidiarrhoeal drug on mouth-to-anus transit-time and duration of diarrhoea in infantle diarrhoea.

The investigators studied mouth-to-anus transit-time (MATT) and duration of diarrhoea (DD) in 40 infants, aged 2 to 24 months, who presented with acute diarrhoea with moderate to severe dehydration. Each patient was put either into Group I, II, III or IV. AII groups received ORS as a rehydrating solution (with carmine red in the first dose of ORS ). Groups II, III and IV were given lacteol fort, smectite and kaloin-pectin, respectively, in addition to ORS. The investigators found no significant difference among the four groups in terms of MATT and DD. It is concluded that the addition of anti-diarrhoeal drugs to ORS in infants with diarrhoea had no significant difference in terms of MATT and DD.